The Ultimate Regenerative Facial: Choose Your Powerful Active After Clinical Prep
Updated: Oct 26
At Captulina, every facial is designed as a precise sequence of preparation and delivery. We begin with a thorough double cleanse under steam, carefully prep and perform extractions, tone the skin, and apply high-frequency treatment. We then ready the skin with LED light therapy before using spicules to stimulate collagen and deeply infuse one powerful regenerative active of your choice: freeze-dried pure PDRN (BR Pharm / PN CELL), ExoHealer umbilical cord blood exosomes, or Channel Pro Power Blue GHK-Cu + NAD+.
TL;DR
Captulina pairs clinical preparation with one powerful regenerative active chosen for your skin goals.
Comparing a PDRN facial vs exosome facial? PDRN focuses on calming repair; ExoHealer targets density and luminosity.
Channel Pro Power Blue GHK-Cu + NAD+ focuses on remodeling, firmness, and cellular energy.
The sequence includes double cleansing, extractions, toning, high-frequency treatment, LED, and spicule delivery.
This is not a surface treatment. It is a clinical protocol that clears congestion, calms inflammation, and activates the skin’s natural repair processes—then delivers a high-potency ingredient into freshly prepared skin so it can work at a deeper level. You select the active that best matches your skin goals.
Choose Your Regenerative Active
Active | Focus | Best for |
Freeze-Dried Pure PDRN (BR Pharm / PN CELL) | Repair, calming, and barrier support | Congested or sensitive skin, early aging, and post-extraction recovery |
ExoHealer Umbilical Cord Blood Exosomes (Filcore / P198) | Regenerative signaling, density, and luminosity | Mature, dull, or textured skin and advanced regenerative goals |
Channel Pro Power Blue GHK-Cu + NAD+ | Remodeling, firmness, and cellular energy | Texture improvement, collagen stimulation, and post-extraction recovery |
Option 1: Freeze-Dried Pure PDRN (BR Pharm / PN CELL)
PDRN (polydeoxyribonucleotide) is a highly purified fraction of salmon DNA. In its freeze-dried pure form, the ingredients remain stable and preservative-free until the moment of use.
PDRN supports the skin’s natural repair processes by activating the adenosine A2A receptor pathway. It is valued for:
Accelerating tissue repair and regeneration.
Reducing inflammation and redness.
Supporting fibroblast activity and collagen synthesis.
Improving skin elasticity and barrier function.
Helping calm post-procedure or post-extraction skin.
Best for: Congested or acne-prone skin after extractions, barrier-compromised or sensitive skin, early aging, and anyone seeking calm, regenerative repair.
Option 2: ExoHealer Umbilical Cord Blood Exosomes (Filcore / P198)
Exosomes derived from umbilical cord blood stem cell conditioned media are among the youngest and most potent regenerative signals available. ExoHealer delivers an exceptionally high concentration of these nanovesicles along with key growth factors, including EGF, VEGF, IGF, KGF, and others.
These tiny messengers help:
Communicate repair instructions to skin cells.
Support collagen and elastin production.
Reduce inflammation and accelerate recovery.
Improve skin density, luminosity, and overall vitality.
Address multiple concerns at once—dullness, fine lines, texture, and post-inflammatory marks.
Best for: Mature or aging skin seeking density and firmness, dull or textured skin, and advanced regenerative goals.
Option 3: Channel Pro Power Blue GHK-Cu + NAD+
This distinctive blue serum combines two complementary actives. GHK-Cu (copper tripeptide-1) is a well-studied peptide that signals the skin to remodel and rebuild. NAD+ supports cellular energy and DNA repair pathways.
Together they:
Stimulate collagen and elastin synthesis.
Promote wound healing and tissue remodeling.
Reduce inflammation and support barrier recovery.
Improve skin firmness, texture, and resilience.
Help the skin maintain better cellular energy for ongoing repair.
Best for: Skin needing remodeling and firmness, post-extraction recovery, texture improvement, and clients focused on collagen stimulation and cellular energy.
Which Skin Types Benefit Most?
The clinical preparation works beautifully across skin types. The final active is then chosen to match your specific concerns:
Aging or mature skin — often thrives with ExoHealer exosomes or GHK-Cu + NAD+ for density and remodeling.
Congested or acne-prone skin that has undergone extractions — frequently benefits from PDRN or GHK-Cu + NAD+ for calming and repair.
Dull or textured skin — responds well to any of the three, with the choice depending on whether the priority is luminosity, firmness, or barrier support.
Sensitive or barrier-compromised skin — typically does best with PDRN’s gentle regenerative action.
Post-procedure or recovery-focused skin — all three support healing; the selection depends on the desired emphasis.
Clients with active infection, open wounds, or certain medical conditions should always be evaluated individually, but the majority of skin types—especially those with visible congestion, early aging, or recovery needs—respond beautifully when the right active is selected.
How the Facial Protocol Maximizes Results
The sequence is intentional. Every step prepares the skin so the final infusion of your chosen active can perform at its highest potential.
1. Thorough Double Cleanse with Steam
We begin by removing makeup, sunscreen, and surface debris, then use steam to soften the skin and open pores. This creates a clean, receptive canvas and makes extractions more comfortable and effective.
2. Preparation and Extractions
Congestion is carefully cleared. Removing comedones and impurities eliminates a major source of inflammation and allows subsequent treatments to reach clearer skin.
3. Toning
The skin is balanced and soothed, reducing residual bacteria and preparing the surface for high-frequency treatment.
4. High-Frequency
High-frequency oxygenates the skin and helps reduce bacteria. This step is especially valuable after extractions, creating a cleaner environment before the regenerative active is applied.
5. LED Light Therapy
LED is used to further calm inflammation, support cellular energy, and enhance the skin’s readiness for the final infusion. Different wavelengths can target redness, healing, or collagen stimulation depending on the client’s needs.
6. Spicule Delivery of Your Chosen Active
Spicules create controlled micro-channels that both stimulate collagen and dramatically improve the absorption of the selected ingredient. Immediately after LED, we apply either freeze-dried pure PDRN, ExoHealer umbilical cord blood exosomes, or Channel Pro Power Blue GHK-Cu + NAD+.
The spicules help drive the active deeper so it can support repair, collagen production, and cellular renewal while the skin is in its most receptive state.
The result is a facial that clears, calms, and regenerates in one session. Clients typically notice smoother texture, reduced redness, improved luminosity, and a healthier overall appearance, with continued improvement in firmness and resilience over the following days and weeks.
Why This Approach Is Different
Many facials stop at cleansing and extractions. Others apply a single serum without proper preparation. This protocol does both: it thoroughly addresses congestion and bacteria, then uses spicules and LED to create optimal conditions for one of three highly researched regenerative ingredients:
PDRN for repair and anti-inflammation.
Umbilical cord blood exosomes for multi-dimensional signaling and collagen support.
GHK-Cu + NAD+ for remodeling and cellular energy.
When these steps are performed in the correct order and the active is matched to your skin, the ingredient does not simply sit on the surface. It is delivered into skin that has been cleaned, calmed, and primed to use it.
If you are looking for a facial that goes beyond temporary glow—one that clears congestion, supports recovery, and actively promotes collagen and cellular repair with a targeted active of your choice—this is the treatment designed for that goal. Book your session at Captulina to experience the full protocol and select the regenerative ingredient that best fits your skin.
Choose Your Powerful Regenerative Active
Book your session at Captulina to experience the full protocol and select the regenerative ingredient that best fits your skin.
FAQ
How do I choose a PDRN facial vs exosome facial?
Choose the active that best matches your skin goals. PDRN focuses on calming, repair, and barrier support, while ExoHealer exosomes focus on density, luminosity, and advanced regenerative goals.
Can I choose GHK-Cu + NAD+ for my facial?
Yes. Channel Pro Power Blue GHK-Cu + NAD+ is an option for skin needing remodeling, firmness, texture improvement, and cellular energy support.
Does the facial use all three actives?
The facial uses one regenerative active of your choice after clinical preparation: freeze-dried pure PDRN, ExoHealer umbilical cord blood exosomes, or Channel Pro Power Blue GHK-Cu + NAD+.
What happens before the selected active is applied?
The protocol begins with a thorough double cleanse under steam, preparation and extractions, toning, high-frequency treatment, and LED light therapy. Spicules are then used to deliver your chosen active.
Which active is recommended for sensitive or barrier-compromised skin?
Sensitive or barrier-compromised skin typically does best with PDRN’s gentle regenerative action. Clients with active infection, open wounds, or certain medical conditions should always be evaluated individually.
What results do clients typically notice?
Clients typically notice smoother texture, reduced redness, improved luminosity, and a healthier overall appearance, with continued improvement in firmness and resilience over the following days and weeks.
One Last Thing
Thorough preparation comes first. Your powerful, personalized active follows. Your skin will thank you for the thorough preparation and the powerful, personalized active that follows.



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